Progranulin variants

Provided herein are progranulin variants and fusion proteins that comprise a progranulin variant and an Fc polypeptide. Methods of using such proteins to treat progranulin-associated disorders (

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Bibliographic Details
Main Authors PROROK, Rachel, KANNAN, Gunasekaran, SRIVASTAVA, Ankita, LOW, Ray L.Y, CHERF, Gerald Maxwell, LEXA, Katrina W
Format Patent
LanguageEnglish
Published 21.12.2023
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Provided herein are progranulin variants and fusion proteins that comprise a progranulin variant and an Fc polypeptide. Methods of using such proteins to treat progranulin-associated disorders (
Bibliography:Application Number: AU20200411480