Improved synthesis of KRAS G12C inhibitor compound
The present disclosure relates to an improved, efficient, scalable process to prepare intermediate compounds, such as 2-isopropyl-4-methylpyridin-3-amine, useful for the synthesis of compounds, such as Compound 9, for the treatment of KRAS G12C mutated cancers.
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Main Authors | , |
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Format | Patent |
Language | English |
Published |
05.05.2022
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Subjects | |
Online Access | Get full text |
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Summary: | The present disclosure relates to an improved, efficient, scalable process to prepare intermediate compounds, such as 2-isopropyl-4-methylpyridin-3-amine, useful for the synthesis of compounds, such as Compound 9, for the treatment of KRAS G12C mutated cancers. |
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Bibliography: | Application Number: AU20200383535 |