Anti-CD53 compositions and methods for modulating myeloid cell inflammatory phenotypes and uses thereof
The present invention is based, in part, on the discovery of anti-CD53 compositions ( e.g., monoclonal antibodies and antigen-binding fragments thereof), that regulate inflammatory phenotypes of myeloid cells, such as suppressive myeloid cells, monocytes, macrophages, neutrophils, and/or dendritic c...
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Main Authors | , , , |
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Format | Patent |
Language | English |
Published |
17.02.2022
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention is based, in part, on the discovery of anti-CD53 compositions ( e.g., monoclonal antibodies and antigen-binding fragments thereof), that regulate inflammatory phenotypes of myeloid cells, such as suppressive myeloid cells, monocytes, macrophages, neutrophils, and/or dendritic cells, including polarization, activation, and/or function, and methods of using such anti-CD53 compositions for therapeutic, diagnostic, prognostic, and screening purposes. |
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Bibliography: | Application Number: AU20200304415 |