Monoclonal antibody that binds specifically to GITR

• Main Authors: GORDEEV, Aleksandr Andreevich, USTIUGOV, Iakov Iurevich, TSYMPILOV, Vladimir Sergeevich, ISHUTINOVA, Anastasia Nikolaevna, KOZLOVA, Olesya Nikolaevna, SOZONOVA, Aleksandra Aleksandrovna, SOLOVYEV, Valery Vladimirovich, AGEEV, Sergei Andreevich, DORONIN, Aleksandr Nikolaevich, ULITIN, Andrei Borisovich, BURNYSHEVA, Ksenia Mihailovna, MITROSHIN, Ivan Vladimirovich, MOROZOV, Dmitry Valentinovich, IVANOV, Roman Alekseevich
• Format: Patent
• Language: English
• Published: 23.12.2021
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

The present invention relates to the field of biotechnology, and particularly to antibodies or their antigen-binding fragments, and to the use thereof. More particularly, the present invention relates to monoclonal antibodies that bind specifically to GITR. The invention also relates to a nucleic acid that codes for said antibody or for an antigen-binding fragment thereof, an expression vector, a method for producing the antibody, and the use of said antibody for treating diseases or disorders associated with GITR.