MODIFIED FGF-21 POLYPEPTIDES AND USES THEREOF

Modified FGF-21 polypeptides and uses thereof are provided, for example, for the treatment of diseases associated with fibrosis. Modified FGF-21 polypeptides are disclosed that contain an internal deletion and optionally replacement peptide, optionally modified with at least one non-naturally-encode...

Full description

Saved in:
Bibliographic Details
Main Authors Morin, Paul E, Cohen, Daniel, Mukherjee, Ranjan, Reilly, Timothy P, Christian, Rose C, Lipovsek, Dasa, Camphausen, Ray, Krupinski, John
Format Patent
LanguageEnglish
Published 13.08.2020
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

More Information
Summary:Modified FGF-21 polypeptides and uses thereof are provided, for example, for the treatment of diseases associated with fibrosis. Modified FGF-21 polypeptides are disclosed that contain an internal deletion and optionally replacement peptide, optionally modified with at least one non-naturally-encoded amino acid, and/or optionally fused to a fusion partner.
Bibliography:Application Number: AU20200210152