Methods of producing high diversity peptide libraries and promoting protein folding

The disclosure provides a peptide library with increased peptide diversity. The increase in peptide diversity can occur via cleavage of particular amino acids within a peptide. The disclosure further provides a method for promoting folding of a peptide into an active conformation.

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Bibliographic Details
Main Authors ROSCOE, Benjamin Peter, AFZELIUS, Ellen Lovisa Larsdotter, YOSEFSON, Ohad, ROGOV, Peter Lyubomirov, MABRY III, George Robert, SWAIN, Joanna Feltham, VAIDYA, Harsh Jayeshkumar
Format Patent
LanguageEnglish
Published 15.07.2021
Subjects
CHEMISTRY
COMBINATORIAL CHEMISTRY
LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:The disclosure provides a peptide library with increased peptide diversity. The increase in peptide diversity can occur via cleavage of particular amino acids within a peptide. The disclosure further provides a method for promoting folding of a peptide into an active conformation.
Bibliography:Application Number: AU20200204988