Oil-based adjuvants

The instant invention provides various formulations comprising combinations of immunostimulating oligonucleotides, polycationic carriers, sterols, saponins, quaternary amines, TLR-3 agonists, glycolipids, and MPL-A or analogs thereof in oil emulsions, use thereof in preparations of immunogenic compo...

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Main Authors Gallo, Guillermo, Foss, Dennis L, Mwangi, Duncan, Donachie, William, Smith, David George Emslie, Dominowski, Paul Joseph, Vora, Shaunak, Mahan, Suman, Rai, Sharath K, Krebs, Richard Lee, Hardham, John Morgan, Mediratta, Sangita, Salmon, Sarah A, Mohr, Kaori, Lightle, Sandra Ann Marie, Jaglarz, Anita Dorota, Wilmes, Lauren, Fontaine, Michael Christopher, Fitzpatrick, Julie Lydia
Format Patent
LanguageEnglish
Published 08.12.2022
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The instant invention provides various formulations comprising combinations of immunostimulating oligonucleotides, polycationic carriers, sterols, saponins, quaternary amines, TLR-3 agonists, glycolipids, and MPL-A or analogs thereof in oil emulsions, use thereof in preparations of immunogenic compositions and vaccines, and use thereof in the treatment of animals.
Bibliography:Application Number: AU20200202147