Novel rationally designed protein compositions

Novel compositions and methods relating to or derived from a rationally designed fusion protein composition combines a therapeutic antibody with an IL2 mutant that can simultaneously enhance anti-tumor immunity or derepress tumor-associated immunosuppression along with direct activation of effector...

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Bibliographic Details
Main Authors LAU, Alan, LI, Chiang J, UNNIRAMAN, Shyam, BADER, Hannah
Format Patent
LanguageEnglish
Published 03.06.2021
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Summary:Novel compositions and methods relating to or derived from a rationally designed fusion protein composition combines a therapeutic antibody with an IL2 mutant that can simultaneously enhance anti-tumor immunity or derepress tumor-associated immunosuppression along with direct activation of effector cells by IL2 without activating T
Bibliography:Application Number: AU20190371994