Boron containing PDE4 inhibitors

The present invention relates to boron containing compounds of Formula (I) X-Y-Z Formula (I) that inhibit phosphodiesterase 4 (PDE4). The invention also encompasses pharmaceutical compositions containing these compounds and methods for treating diseases, conditions, or disorders ameliorated by inhib...

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Bibliographic Details
Main Authors ODERINDE, Martins Sunday, STROHBACH, Joseph Walter, JONES, Peter, YEOH, Thean Yeow, PLATTNER, Jacob John, JACOBS, Robert Toms, PERRY, Matthew Alexander, BLAKEMORE, David Clive, LIMBURG, David Christopher, AKAMA, Tsutomu, TORELLA, Rubben Federico, ZHOU, Yasheen
Format Patent
LanguageEnglish
Published 28.07.2022
Subjects
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to boron containing compounds of Formula (I) X-Y-Z Formula (I) that inhibit phosphodiesterase 4 (PDE4). The invention also encompasses pharmaceutical compositions containing these compounds and methods for treating diseases, conditions, or disorders ameliorated by inhibition of PDE4.
Bibliography:Application Number: AU20190351960