AGONIST OF SPEXIN-BASED GALANIN TYPE 2 RECEPTOR AND USE THEREOF

The present invention relates to spexin-based agonists specific for galanin receptor type 2 and use thereof. More specifically, the present invention provides 5 peptide-based agonists with high specificity for galanin receptor type 2 and improved stability. The peptide-based agonists are involved in...

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Bibliographic Details
Main Authors Lee, Yoo-Na, Yun, Seongsik, Reyes-alcaraz, Arfaxad, Kim, Dong-Hoon, Son, Gi Hoon, Seong, Jae Young, Hwang, Jong-Ik
Format Patent
LanguageEnglish
Published 30.04.2020
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention relates to spexin-based agonists specific for galanin receptor type 2 and use thereof. More specifically, the present invention provides 5 peptide-based agonists with high specificity for galanin receptor type 2 and improved stability. The peptide-based agonists are involved in the regulation of in vivo physiological functions, such as food intake, anxiety, emotion, and addiction, for which galanin receptors type 2 is responsible, to effectively suppress appetite, help recover from anxiety disorder, and reduce pleasure addiction. Therefore, the peptide-based 10 agonists can be used to prevent or treat galanin receptor type 2-mediated diseases.
Bibliography:Application Number: AU20190202918