Carboxamides as modulators of sodium channels

Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharm...

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Main Authors HURLEY, Dennis, ANDERSON, Corey, CAMP, Joanne Louise, HADIDA RUAH, Sara Sabina, ARUMUGAM, Vijayalaksmi, ASGIAN, Iuliana Luci, MEIRELES, Lidio Marx Carvalho, FANNING, Lev Tyler Dewey, AHMAD, Nadia, THOMSON, Stephen Andrew, SHAW, David, SHETH, Urvi, SCHMIDT, Yvonne
Format Patent
LanguageEnglish
Published 30.01.2020
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.
Bibliography:Application Number: AU20180300150