Methods and pharmaceutical compositions for the treatment of hepatitis B virus infection

• Main Authors: ROCHE, Didier, ANDRE, Patrice, HALLAKOU-BOZEC, Sophie, RADREAU, Pauline, GILARDONE, Marine, CRAVO, Daniel, PATIN, Amaury, LOTTEAU, Vincent
• Format: Patent
• Language: English
• Published: 20.12.2018
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF HEPATITIS B VIRUS INFECTION Abstract The present invention relates to methods and pharmaceutical compositions for the treatment of hepatitis B virus infection. In particular, the present invention relates to a method for treating a chronic hepatitis B virus infection in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a farnesoid X receptor (FXR) agonist, as well as the use of farnesoid X receptor (FXR) agonist for the manufacture of a medicament for treating a chronic hepatitis B virus infection in a subject in need thereof.