Kappa opioid receptor antagonists and products and methods related thereto

Compounds are provided that antagonize the kappa-opioid receptor (KOR) and products containing such compounds, as well as to methods of their use and synthesis. Such compounds have the structure of Formula (I), or a pharmaceutically acceptable isomer, racemate, hydrate, solvate, isotope or salt ther...

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Main Authors Urbano, Mariangela, Laxamana, Candace Mae, Jones, Robert M, Roberts, Edward, Turtle, Eric Douglas, Rosen, Hugh, Zhao, Xianrui, Guerrero, Miguel A
Format Patent
LanguageEnglish
Published 26.05.2022
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Summary:Compounds are provided that antagonize the kappa-opioid receptor (KOR) and products containing such compounds, as well as to methods of their use and synthesis. Such compounds have the structure of Formula (I), or a pharmaceutically acceptable isomer, racemate, hydrate, solvate, isotope or salt thereof: (I) wherein X, Y, R
Bibliography:Application Number: AU20180234931