Processes and intermediates for preparing a medicament

Abstract PROCESSES AND INTERMEDIATES FOR PREPARING A MEDICAMENT Disclosed is a process for the preparation of the following compounds: R 2a 0 where R', R" and R2a have the definitions in the description, as well as a process to prepare other intermediates that may be useful to synthesise d...

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Bibliographic Details
Main Authors Pye, Philip, Houpis, Ioannis Nicolaos, Conza, Matteo, Ben Haim, Cyril
Format Patent
LanguageEnglish
Published 12.03.2020
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Abstract PROCESSES AND INTERMEDIATES FOR PREPARING A MEDICAMENT Disclosed is a process for the preparation of the following compounds: R 2a 0 where R', R" and R2a have the definitions in the description, as well as a process to prepare other intermediates that may be useful to synthesise downstream products, especially compounds that are useful as medicaments, for instance Bruton's tyrosine kinase (Btk) inhibitors such as ibrutinib. Also disclosed are other processes, other 15 intermediates and compounds per se.
Bibliography:Application Number: AU20180204086