N-phenyl-carboxamide derivatives and the use thereof as medicaments for the treatment of Hepatitis B

Abstract N-PHENYL-CARBOXAMIDE DERIVATIVESAND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B Inhibitors of HBV replication of Formula (I) 1i R2 R4 XN N >GR3 including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein X, R', R2 , R3 and R4 have th...

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Bibliographic Details
Main Authors Raboisson, Pierre Jean-Marie Bernard, Hache, Geerwin Yvonne Paul, Last, Stefaan Julien, Vandyck, Koen
Format Patent
LanguageEnglish
Published 21.11.2019
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Abstract N-PHENYL-CARBOXAMIDE DERIVATIVESAND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B Inhibitors of HBV replication of Formula (I) 1i R2 R4 XN N >GR3 including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein X, R', R2 , R3 and R4 have the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other HBV inhibitors, in HBV therapy.
Bibliography:Application Number: AU20180204027