Tetraazabicyclo-macrocycle based manganese chelate compounds suitable as MRI imaging agents

The invention provides compounds of formula (I) representing a polyaza-macrocycle with carboxylic acid side arms complexing Manganese as core metal. The complexes are suitable for use as contrast agents in magnetic resonance imaging (MRI).

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Bibliographic Details
Main Authors Bales, Brian Christopher, Thaning, Mikkel Jacob, Rishel, Michael James, Meijer, Andreas Richard
Format Patent
LanguageEnglish
Published 12.09.2019
Subjects
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention provides compounds of formula (I) representing a polyaza-macrocycle with carboxylic acid side arms complexing Manganese as core metal. The complexes are suitable for use as contrast agents in magnetic resonance imaging (MRI).
Bibliography:Application Number: AU20170382953