Oral vaccine against ruminant respiratory disease comprising polyvinylpyrrolidone

The present invention relates to an oral vaccine against respiratory disease in ruminants, comprising live attenuated Mannheimia haemolytica bacteria and a Polyvinylpyrrolidone (PVP). The addition of PVP significantly improves the protective effect of vaccination on lung scores after a challenge inf...

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Bibliographic Details
Main Authors O'Connell, Kevin, Vaidyanathan, Subramaniam, Eddy, Brad
Format Patent
LanguageEnglish
Published 30.05.2019
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention relates to an oral vaccine against respiratory disease in ruminants, comprising live attenuated Mannheimia haemolytica bacteria and a Polyvinylpyrrolidone (PVP). The addition of PVP significantly improves the protective effect of vaccination on lung scores after a challenge infection. Further the PVP allows vaccination by a method of mass administration, such as by oral route via a drink. In addition the invention relates to methods for the preparation of such a vaccine, to methods for the vaccination of ruminants employing such a vaccine, and to medical uses of a composition comprising M. haemolytica bacteria.
Bibliography:Application Number: AU20170375720