Azabenzimidazole derivatives as PI3K beta inhibitors

The present invention relates to azabenzimidazole derivatives of Formula (I) (I) wherein the variables have the meaning defined in the claims. The compounds according to the present invention are useful as pI3Kβ inhibitors. The invention further relates to pharmaceutical compositions comprising said...

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Bibliographic Details
Main Authors Querolle, Olivier Alexis Georges, Meerpoel, Lieven, Berthelot, Didier Jean-Claude, Mercey, Guillaume Jean Maurice, Demestre, Christophe Gabriel Marcel, Pasquier, Elisabeth Thérèse Jeanne, Angibaud, Patrick René, Pilatte, Isabelle Noëlle Constance, Mevellec, Laurence Anne, Poncelet, Virginie Sophie, Coupa, Sophie, Meyer, Christophe
Format Patent
LanguageEnglish
Published 06.12.2018
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to azabenzimidazole derivatives of Formula (I) (I) wherein the variables have the meaning defined in the claims. The compounds according to the present invention are useful as pI3Kβ inhibitors. The invention further relates to pharmaceutical compositions comprising said compounds as an active 10 ingredient as well as the use of said compounds as a medicament.
Bibliography:Application Number: AU20170286380