Angiotensin-1-receptor antagonists

In one aspect, this disclosure features compounds of formula (I)or a pharmaceutically acceptable salt thereof: AA1-Arg-Val-AA4-AA5-His-Pro-AA8-OH(I), in which AA1, AA4, AA5, and AA8 are defined in the specification. The compounds of formula (I) can be used to treat hypertension(e.g., hypertension in...

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Bibliographic Details
Main Authors Stalewski, Jacek, Cable, Edward Earl
Format Patent
LanguageEnglish
Published 01.04.2021
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:In one aspect, this disclosure features compounds of formula (I)or a pharmaceutically acceptable salt thereof: AA1-Arg-Val-AA4-AA5-His-Pro-AA8-OH(I), in which AA1, AA4, AA5, and AA8 are defined in the specification. The compounds of formula (I) can be used to treat hypertension(e.g., hypertension induced by pregnancy), preeclampsia,or a renal disease induced bypregnancy.
Bibliography:Application Number: AU20170275748