TNF superfamily collectin fusion proteins

TNF SUPERFAMILY COLLECTIN FUSION PROTEINS The present invention refers to a fusion protein comprising a TNF- superfamily (TNFSF) cytokine or a receptor binding thereof fused a collectin trimerization domain, to a nucleic acid molecule encoding the fusion protein, and to a cell comprising the nucleic...

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Bibliographic Details
Main Authors GIFFERS, Christian, BRANSCHADEL, Marcus, THIEMANN, Meinolf, HILL, Oliver
Format Patent
LanguageEnglish
Published 22.03.2018
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:TNF SUPERFAMILY COLLECTIN FUSION PROTEINS The present invention refers to a fusion protein comprising a TNF- superfamily (TNFSF) cytokine or a receptor binding thereof fused a collectin trimerization domain, to a nucleic acid molecule encoding the fusion protein, and to a cell comprising the nucleic acid molecule. The fusion protein is present as a trimeric complex or as an oligomer thereof. The fusion protein, the nucleic acid, and the cell is suitable as pharmaceutical composition or for therapeutic, diagnostic and/or research applications.
Bibliography:Application Number: AU20170201232