NAMPT and ROCK Inhibitors

NAMPT AND ROCK INHIBITORS Disclosed are compounds of formula (1c) which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed. Disclosed are compounds which inhibit the activity of ROCK, compositions containing the compo...

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Main Authors CURTIN, Michael L, HEYMAN, Howard R, WOLLER, Kevin R, SHAH, Omar J, SWEIS, Ramzi, VASUDEVAN, Anil, SORENSEN, Bryan K, HANSEN, Todd M, CLARK, Richard F, PLIUSHCHEV, Marina A, MICHAELIDES, Michael, TSE, Chris, MACK, Helmut
Format Patent
LanguageEnglish
Published 02.02.2017
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:NAMPT AND ROCK INHIBITORS Disclosed are compounds of formula (1c) which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed. Disclosed are compounds which inhibit the activity of ROCK, compositions containing the compounds and methods of treating diseases during which ROCK is expressed.
Bibliography:Application Number: AU20170200079