Substituted triazolopiperazine PARP inhibitor, preparation method therefor, and use thereof

The present invention relates to a class of substituted triazolopiperazine compounds represented by general formula (I), tautomers, enantiomers, diastereomers, racemates, metabolites, metabolic precursors, and pharmaceutically acceptable salts, esters, prodrugs or hydrates thereof, a preparation met...

Full description

Saved in:
Bibliographic Details
Main Authors Song, Shanshan, Zhang, Ao, Song, Zilan, Huan, Xiajuan, Fan, Zhoulong, Miao, Zehong, Wang, Pingyuan, Ding, Jian
Format Patent
LanguageEnglish
Published 21.06.2018
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:The present invention relates to a class of substituted triazolopiperazine compounds represented by general formula (I), tautomers, enantiomers, diastereomers, racemates, metabolites, metabolic precursors, and pharmaceutically acceptable salts, esters, prodrugs or hydrates thereof, a preparation method therefor, intermediates, and a use thereof in the preparation of drugs for the prevention and treatment of PARP-related disorders, wherein said PARP-related disorders comprise various ischemic diseases, neurodegenerative disorders and cancer.
Bibliography:Application Number: AU20160359511