Virus-like particle with efficient epitope display

The invention relates to a virus-like particle (VLP) based vaccine. The virus-like particle constitutes a non-naturally occurring, ordered and repetitive antigen array display scaffold which can obtain a strong and long-lasting immune response in a subject. The VLP-based vaccine may be used for the...

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Bibliographic Details
Main Authors Theander, Thor, Salanti, Ali, Bertelsen, Adam Frederik Sander, Tobias Gustafsson, Jan, Thrane, Susan, Janitzek, Christoph Mikkel, Ørskov Agerbæk, Mette, Agertoug Nielsen, Morten
Format Patent
LanguageEnglish
Published 04.02.2021
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention relates to a virus-like particle (VLP) based vaccine. The virus-like particle constitutes a non-naturally occurring, ordered and repetitive antigen array display scaffold which can obtain a strong and long-lasting immune response in a subject. The VLP-based vaccine may be used for the prophylaxis and/or treatment of a disease including, but is not limited to, cancer, cardiovascular, infectious, chronic, neurological diseases/disorders, asthma, and/or immune-inflammatory diseases/disorders.
Bibliography:Application Number: AU20160207099