Contiguity preserving transposition

Embodiments provided herein relate to methods and compositions for preparing an immobilized library of barcoded DNA fragments of a target nucleic acid, identifying genomic variants, determining the contiguity information, phasing information, and methylation status of the target nucleic acid.

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Bibliographic Details
Main Authors Betley, Jason Richard, Jenkins, Gareth, Pantoja, Rigo, Zhang, Fan, Weir, Jacqueline, Meuleman, Wouter, Goryshin, Igor, Gunderson, Kevin L, Kia, Amirali, Ioannou, Avgousta, Gormley, Niall Anthony, Morrell, Natalie, Jackson, Rosamond, Norberg, Steven J, He, Molly, Steemers, Frank J, Pokholok, Dmitry K
Format Patent
LanguageEnglish
Published 02.12.2021
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Summary:Embodiments provided herein relate to methods and compositions for preparing an immobilized library of barcoded DNA fragments of a target nucleic acid, identifying genomic variants, determining the contiguity information, phasing information, and methylation status of the target nucleic acid.
Bibliography:Application Number: AU20150331739