Peptide for treatment of type 2 diabetes mellitus and its complications

The invention relates to biotechnology. The exenatide analogue with the formula H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-As -Leu-Ser-Lys-Gln-Glu-Glu-Glu-Glu-Ala-Val-Arg -Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-D-Arg-D-Arg-D-Arg-D- Arg-D-Arg-D-Arg-D-Arg-D-Arg-Gly-OH is p...

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Bibliographic Details
Main Authors Shekunova, Elena Vasilyevna, Makarova, Marina Nikolaevna, Eliseev, Ivan Ivanovich, Kashkin, Vladimir Aleksandrovich, Makarov, Valery Gennadyevich, Titov, Mikhail Ivanovich
Format Patent
LanguageEnglish
Published 10.05.2018
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention relates to biotechnology. The exenatide analogue with the formula H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-As -Leu-Ser-Lys-Gln-Glu-Glu-Glu-Glu-Ala-Val-Arg -Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-D-Arg-D-Arg-D-Arg-D- Arg-D-Arg-D-Arg-D-Arg-D-Arg-Gly-OH is presented. The invention allows treating and taking preventive measures against diabetes mellitus as well as treating and taking preventive measures against type 2 diabetes mellitus complications, such as diabetic neuropathy, muscular dystrophy and endotheliopathy.
Bibliography:Application Number: AU20150304934