TCR libraries

The present invention relates to a library of particles, the library displaying a plurality of different T cell receptors (TCRs), wherein the plurality of TCRs consists essentially of TCRs comprising an alpha chain variable domain from a natural repertoire and a beta chain variable domain from a nat...

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Bibliographic Details
Main Authors VUIDEPOT, ANNELISE BRIGITTE, JAKOBSEN, BENT KARSTEN, LIDDY, NATHANIEL ROSS, MOLLOY, PETER EAMON
Format Patent
LanguageEnglish
Published 15.09.2016
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:The present invention relates to a library of particles, the library displaying a plurality of different T cell receptors (TCRs), wherein the plurality of TCRs consists essentially of TCRs comprising an alpha chain variable domain from a natural repertoire and a beta chain variable domain from a natural repertoire, wherein the alpha chain variable10 domain comprises a TRAV12-2 or a TRAV21 gene product and the beta chain variable domain comprises a TRBV6 gene product.
Bibliography:Application Number: AU20150228751