Substituted pyrimidine compounds and their use as SYK inhibitors

Compounds of Formula (I) and methods for inhibiting kinases, including spleen tyrosine kinases, are disclosed. Also disclosed are methods for treating a kinase-mediated disease or condition by administering to a subject a therapeutically effective amount of the compound of Formula (I).

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Bibliographic Details
Main Authors CHOI, JANG-SIK, HWANG, HAE-JUN, LEE, JAESANG, SUH, BYUNGUL, LEE, JAEKYOO, CHOI, YUNG-GEUN, KIM, SE-WON, LEE, TAE-IM, LEE, IN YONG, JUNG, DONG-SIK, SALGAONKAR, PARESH DEVIDAS, PARK, SUNG-HO, KOH, JONG SUNG, SONG, HO-JUHN, KIM, JUNG-HO
Format Patent
LanguageEnglish
Published 28.04.2016
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Compounds of Formula (I) and methods for inhibiting kinases, including spleen tyrosine kinases, are disclosed. Also disclosed are methods for treating a kinase-mediated disease or condition by administering to a subject a therapeutically effective amount of the compound of Formula (I).
Bibliography:Application Number: AU20140340249