Highly productive simulated moving bed chromatographic separation

The invention is directed to a simulated moving bed chromatographic separation process, and to a simulated moving bed chromatography apparatus for carrying out said process. The simulated moving bed chromatographic separation process of the invention comprises the steps of applying a feed mixture an...

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Bibliographic Details
Main Authors Bussmann, Paulus Josephus Theodorus, Vroon, Ronald Cornelis, Boon, Moniek Afra
Format Patent
LanguageEnglish
Published 28.06.2018
Subjects
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
SEPARATION
TRANSPORTING
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Summary:The invention is directed to a simulated moving bed chromatographic separation process, and to a simulated moving bed chromatography apparatus for carrying out said process. The simulated moving bed chromatographic separation process of the invention comprises the steps of applying a feed mixture and a mobile phase in which said feed mixture is soluble to a simulated moving bed comprising a particulate stationary phase, and separating said feed mixture into an extract and a raffinate, wherein said simulated moving bed comprises multiple radial and/or axial flow columns connected in series into a loop, and wherein the particulate stationary phase of said simulated moving bed has a median particle diameter of 100 mm or less.
Bibliography:Application Number: AU20130360467