Compositions and methods for capture of cellular targets of bioactive agents

The present invention provides compositions and methods for capture and identification of the cellular targets of a bioactive agent. In particular, provided herein are bioactive agents tethered to capture ligand, cellular targets (optionally tagged with a reporter), capture proteins (optionally pres...

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Main Authors URH, MARJETA, HURST, ROBIN, KIRKLAND, THOMAS, NATH, NIDHI, HITKO, CAROLYN W, KLAUBERT, DIETER, MEISENHEIMER, PONCHO, OHANA, RACHEL F, UYEDA, HARRY TETSUO, OTTO, PAUL, WOOD, KEITH
Format Patent
LanguageEnglish
Published 12.11.2015
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention provides compositions and methods for capture and identification of the cellular targets of a bioactive agent. In particular, provided herein are bioactive agents tethered to capture ligand, cellular targets (optionally tagged with a reporter), capture proteins (optionally present as capture fusions), surfaces (e.g., displaying, capture ligands, capture proteins, or capture fusions), and methods of capturing and identifying the cellular targets of a bioactive agent therewith.
Bibliography:Application Number: AU20130359160