Procaspase combination therapy for glioblastoma

The invention provides compositions and methods for the induction of cell death, for example, cancer cell death. Combinations of compounds and related methods of use are disclosed, including the use of compounds in therapy for the treatment of cancer and selective induction of apoptosis in cells. Th...

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Main Authors GILBERT, MARK J, JOSHI, AVADHUT, BOTHAM, RACHEL C, RIGGINS, GREGORY J, HANDLEY, MICHAEL K, TARASOW, THEODORE M, HERGENROTHER, PAUL J, FAN, TIMOTHY M
Format Patent
LanguageEnglish
Published 12.05.2016
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention provides compositions and methods for the induction of cell death, for example, cancer cell death. Combinations of compounds and related methods of use are disclosed, including the use of compounds in therapy for the treatment of cancer and selective induction of apoptosis in cells. The disclosed drug combinations can have lower neurotoxicity effects than other compounds and combinations of compounds.
Bibliography:Application Number: AU20130230985