Single-domain antigen-binding proteins that bind mammalian IgG

The present application relates to antigen-binding proteins that are capable of binding to mammalian IgG. The frame-work regions of the antigen-binding proteins of the application preferably correspond to those of antibodies naturally that are devoid of light chains as may e.g. 5 be found in camelid...

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Bibliographic Details
Main Authors BEZEMER, SANDRA, MIJNSBERGEN, YVONNE MATHALIE, HERMANS, WILHELMUS JOSEPHUS JOHANNA
Format Patent
LanguageEnglish
Published 12.09.2013
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:The present application relates to antigen-binding proteins that are capable of binding to mammalian IgG. The frame-work regions of the antigen-binding proteins of the application preferably correspond to those of antibodies naturally that are devoid of light chains as may e.g. 5 be found in camelids. The application further relates to nucleic acids that encode such antigen binding proteins, to immunoadsorbent materials that comprise such proteins, to the uses of such immunoadsorbent materials for the purification of mammalian IgG antibodies and for therapeutic apheresis.
Bibliography:Application Number: AU20130221940