Hepcidin and Hepcidin Antibodies

The invention relates to purified, correctly folded hepcidin, antibodies that bind hepcidin, and methods of making and using such materials. Also provided are methods of treated hepcidin-related disorders. WO 2008/097461 PCT/US2008/001325 Day: 0 3 3+2hr Ab (sc) IP harvest B 25 pg hepcidin * P < 0...

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Bibliographic Details
Main Authors COOKE, KEEGAN, BI, XIAO-JUAN, WINTERS, AARON, HANIU, MITSURU, SASU, BARBRA, SHENG, ZEGI, ARVEDSON, TARA, BOONE, THOMAS CHARLES, LEE, KI JEONG
Format Patent
LanguageEnglish
Published 12.09.2013
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
TESTING
VINEGAR
WINE
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Summary:The invention relates to purified, correctly folded hepcidin, antibodies that bind hepcidin, and methods of making and using such materials. Also provided are methods of treated hepcidin-related disorders. WO 2008/097461 PCT/US2008/001325 Day: 0 3 3+2hr Ab (sc) IP harvest B 25 pg hepcidin * P < 0.05 ** P <0.01 =saline n=5 =160 n=5 .-lhepcidin + isotype control 140 -*ihepcidin + Ab 2.7 (110pM) 0)100 Ab dosing (mg/mouse) Fig. 11
Bibliography:Application Number: AU20130221906