Prolonged inhibition of interleukin-6 mediated signaling
Polypeptides are provided directed against IL-6R at specific dose ranges and dosing schedules that result in a prolonged effect on IL-6 mediated signaling. In particular, the invention provides pharmacologically active agents, compositions, methods and/or dosing schedules that have certain advantage...
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Main Authors | , , , , |
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Format | Patent |
Language | English |
Published |
01.12.2016
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Subjects | |
Online Access | Get full text |
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Summary: | Polypeptides are provided directed against IL-6R at specific dose ranges and dosing schedules that result in a prolonged effect on IL-6 mediated signaling. In particular, the invention provides pharmacologically active agents, compositions, methods and/or dosing schedules that have certain advantages compared to the agents, compositions, methods and/or dosing schedules that are currently used and/or known in the art, including the ability to dose less frequently or to administer lower doses to obtain eq uivalent effects in inhibiting IL-6 mediated signaling. |
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Bibliography: | Application Number: AU20120311443 |