Morpholine-spirocyclic piperidine amides as modulators of ion channels

The invention relates to morpholine spirocyclic piperidine amide compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

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Bibliographic Details
Main Authors Hilgraf, Nicole, Deninno, Michael Paul, Hurley, Dennis James, Silina, Alina, Sheth, Urvi Jagdishbhai, Binch, Hayley Marie, Frieman, Bryan A, Kallel, Edward Adam, Joshi, Pramod, Arumugam, Vijayalaksmi, Pontillo, Joseph, Grootenhuis, Peter Diederik Jan, Fanning, Lev Tyler Dewey, Miller, Mark Thomas, Hadida-Ruah, Sara Sabina
Format Patent
LanguageEnglish
Published 10.11.2016
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to morpholine spirocyclic piperidine amide compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
Bibliography:Application Number: AU20120229187