Drug-eluting self-retaining sutures and methods relating thereto

A drug-eluting self-retaining suture comprises a filament, a plurality of retainers, and a drug impregnated in or coated on the filament. The shape and distribution of retainers modifies the in vivo release kinetics of the drug. The drug release kinetics may be modified uniformly or region by region...

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Main Authors NELSON, KEVIN DON, DRUBETSKY, LEV, AVELAR, RUI, CROW, BRENT B, GRIFFIN, NICKOLAS B, NAIMAGON, ALEXANDER, GROSS, JEFFREY M, D'AGOSTINO, WILLIAM L
Format Patent
LanguageEnglish
Published 30.06.2016
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Summary:A drug-eluting self-retaining suture comprises a filament, a plurality of retainers, and a drug impregnated in or coated on the filament. The shape and distribution of retainers modifies the in vivo release kinetics of the drug. The drug release kinetics may be modified uniformly or region by region. The self-retaining suture may for example be used for reattaching severed nerves and release nerve growth factor or other regeneration accelerating agents into the region of the nerve injury.
Bibliography:Application Number: AU20110323299