Transdermal therapeutic systems with crystallization-inhibiting protective film (release liner)

The invention relates to pharmaceutical formulations, in particular to transdermal therapeutic systems, which are characterized in that no active substance crystallizes out at the interface between the removable release liner and the active-substance-containing matrix. The active substance is gestod...

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Bibliographic Details
Main Authors BRACHT, STEFAN, TEREBESI, ILDIKO, LANGGUTH, THOMAS
Format Patent
LanguageEnglish
Published 28.03.2013
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention relates to pharmaceutical formulations, in particular to transdermal therapeutic systems, which are characterized in that no active substance crystallizes out at the interface between the removable release liner and the active-substance-containing matrix. The active substance is gestodene or a gestodene ester in supersaturated matrix polymer and/or ethynyl estradiol. The matrix is free from solubilizers, crystallization inhibitors and dispersants.
Bibliography:Application Number: AU20110298892