Pyrrolo- pyrazine derivatives useful as inhibitors of ATR kinase

The present invention relates to pyrrolopyrazines compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the comp...

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Main Authors MACCORMICK, SOMHAIRLE, VIRANI, ANIZA NIZARALI, KNEGTEL, RONALD MARCELLUS ALPHONSUS, FRAYSSE, DAMIEN, CHARRIER, JEAN-DAMIEN, DURRANT, STEVEN JOHN, PINDER, JOANNE, REAPER, PHILIP MICHAEL
Format Patent
LanguageEnglish
Published 31.01.2013
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to pyrrolopyrazines compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in
Bibliography:Application Number: AU20110270807