Arylmethoxy isoindoline derivatives and compositions comprising and methods of using the same

Provided are 4'-arylmethoxy isoindoline compounds, and pharmaceutically acceptable salts, solvates, clathrates, stereoisomers, and prodrugs thereof. Methods of use, and pharmaceutical compositions of these compounds are disclosed. The compounds are derivatives of hydroxy thalidomide active agai...

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Main Authors ZHANG, WEIHONG, MULLER, GEORGE W, CHEN, ROGER SHENU, MAN, HON-WAH, RUCHELMAN, ALEXANDER, KHALIL, EHAB M
Format Patent
LanguageEnglish
Published 07.11.2013
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Provided are 4'-arylmethoxy isoindoline compounds, and pharmaceutically acceptable salts, solvates, clathrates, stereoisomers, and prodrugs thereof. Methods of use, and pharmaceutical compositions of these compounds are disclosed. The compounds are derivatives of hydroxy thalidomide active against cancer.
Bibliography:Application Number: AU20110215877