Fluorescent imaging with substituted cyanine dyes

Compounds and methods are disclosed that are useful for noninvasive imaging in the near-infrared spectral range. The cyanine compounds of Formula (I) are presented: (I). wherein Q is a portion of a polymethine bridge selected from the group consisting of: (a) and (b). Also included are bioconjugates...

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Bibliographic Details
Main Authors DRANEY, DANIEL R, XU, XINSHE
Format Patent
LanguageEnglish
Published 10.11.2011
Subjects
ADHESIVES
BANDAGES, DRESSINGS OR ABSORBENT PADS
CHEMISTRY
DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS
DYES
FILTERS IMPLANTABLE INTO BLOOD VESSELS
FIRST-AID KITS
FOMENTATION
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
LAKES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MISCELLANEOUS APPLICATIONS OF MATERIALS
MISCELLANEOUS COMPOSITIONS
MORDANTS
NATURAL RESINS
ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES
ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES
PAINTS
PHYSICS
POLISHES
PROSTHESES
TESTING
TREATMENT OR PROTECTION OF EYES OR EARS
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Summary:Compounds and methods are disclosed that are useful for noninvasive imaging in the near-infrared spectral range. The cyanine compounds of Formula (I) are presented: (I). wherein Q is a portion of a polymethine bridge selected from the group consisting of: (a) and (b). Also included are bioconjugates of the compounds of Formula (I), methods of labeling biomolecules with the compounds, and methods of imaging.
Bibliography:Application Number: AU20100236189