Dipeptidyl peptidase IV inhibitors

Described are novel compounds of the Formula (I), their derivatives, analogs, tautomeric forms, regioisomers, stereoisomers, polymorphs, solvates, intermediates, pharmaceutically acceptable salts, pharmaceutical compositions, metabolites and prodrugs thereof. These compounds are effective in lowerin...

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Main Authors SAKAMURI, SUKUMAR, POOPPADY XAVIER, FRANKLIN, RAJALINGAM, AGNEESWARI, KULATHINGAL, JAYANARAYAN, NARAYANAN, SHRIDHAR, DHARMALINGAM, SIVANESAN, MOOKKAN, JEYAMURUGAN, BALASUBRAMANIAN, GOPALAN, BALASUBRAMANIAN, JEGANATHA SIVAKUMAR, SINGH, GAJENDRA
Format Patent
LanguageEnglish
Published 16.02.2012
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Described are novel compounds of the Formula (I), their derivatives, analogs, tautomeric forms, regioisomers, stereoisomers, polymorphs, solvates, intermediates, pharmaceutically acceptable salts, pharmaceutical compositions, metabolites and prodrugs thereof. These compounds are effective in lowering blood glucose, serum insulin, free fatty acids, cholesterol, triglyceride levels; treatment of obesity, inflammation, autoimmune diseases such as multiple sclerosis, rheumatoid arthritis; treatment and/or prophylaxis of type II diabetes. These compounds are more particularly dipeptidyl peptidase (DPP IV) inhibitors.
Bibliography:Application Number: AU20100204144