Compositions and methods of use for soluble thrombomodulin variants

The present invention provides a method for preventing and/or treating a patient with acute kidney injury caused by a variety of conditions. The method comprises administering to the patient soluble thrombomodulin variants that do not bind thrombin. In conjunction with standard of care, soluble thro...

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Bibliographic Details
Main Authors BRIAN WILLIAM GRINNELL, DAVID THOMPSON BERG, AKANKSHA GUPTA
Format Patent
LanguageEnglish
Published 20.05.2010
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Summary:The present invention provides a method for preventing and/or treating a patient with acute kidney injury caused by a variety of conditions. The method comprises administering to the patient soluble thrombomodulin variants that do not bind thrombin. In conjunction with standard of care, soluble thrombomodulin variants that do not bind thrombin will prevent or reduce acute kidney injury and subsequent morbidity and mortality.
Bibliography:Application Number: AU20090314413