Stable polymorph of N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine hydrochloride, methods of production, and pharmaceutical uses thereof

The invention provides a compound comprising N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine, or a pharmaceutically acceptable salt thereof in anhydrous or hydrate form for use in the treatment of NSCLC (non small cell lung cancer).

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Bibliographic Details
Main Authors TIMOTHY NORRIS, JEFFREY W. RAGGON, BARBARA A. FOSTER, KAREN J. FERRANTE, RICHARD D. CONNELL, JAMES D. MOYER, SHAMA M. KAJIJI, SANDRA L. SILBERMAN, MICHAEL J. MORIN
Format Patent
LanguageEnglish
Published 21.01.2010
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SEPARATION
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
TRANSPORTING
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Summary:The invention provides a compound comprising N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine, or a pharmaceutically acceptable salt thereof in anhydrous or hydrate form for use in the treatment of NSCLC (non small cell lung cancer).
Bibliography:Application Number: AU20090251148