Bridged, bicyclic heterocyclic or spiro bicyclic heterocyclic derivatives of pyrazolo[1,5-a]pyrimidines, methods for preparation and uses thereof

Compounds of formula A: and pharmaceutically acceptable salts thereof are described, which selectively inhibit Raf kinase activity and are useful for treating disorders mediated by Raf kinases.

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Bibliographic Details
Main Authors MINU DHANJISH DUTIA, JEREMY IAN LEVIN, DAN MAARTEN BERGER, DARRIN WILLIAM HOPPER, NANCY TORRES, MARTIN JOSEPHGRANDI, XIAOLUN WANG, CHUNCHUN ZHANG, ALEJANDRO LEE DUNNICK
Format Patent
LanguageEnglish
Published 03.09.2009
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Compounds of formula A: and pharmaceutically acceptable salts thereof are described, which selectively inhibit Raf kinase activity and are useful for treating disorders mediated by Raf kinases.
Bibliography:Application Number: AU20090219175