Pyrimidine derivatives useful as Raf kinase inhibitors

The present invention provides compounds useful as inhibitors of Raf protein kinase. The present invention also provides compositions thereof, and methods of treating Raf-mediated diseases.

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Bibliographic Details
Main Authors COSSROW, JENNIFER, TANAKA, HIROKO, VESSELS, JEFFREY, JONES, JOHN HOWARD, LITTKE, ADAM, RAIMUNDO, BRIAN, PENG, HAIRUO, KUMARAVEL, GNANASAMBANDAM, XIN, ZHILI, GUAN, BING, POWELL, NOEL, CHEN, WEIRONG, WYNN, THOMAS, LANE, BENJAMIN, FRANKLIN, LIOYD, LUGOVSKOY, ALEXEY
Format Patent
LanguageEnglish
Published 03.10.2013
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides compounds useful as inhibitors of Raf protein kinase. The present invention also provides compositions thereof, and methods of treating Raf-mediated diseases.
Bibliography:Application Number: AU20080273002