Optimized CD40 antibodies and methods of using the same
The present invention describes antibodies that target CD40, wherein the antibodies comprise at least one modification relative to a parent antibody, wherein the modification alters affinity to an FcyR or alters effector function as compared to the parent antibody. Also disclosed are methods of usin...
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Main Authors | , , , , , , |
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Format | Patent |
Language | English |
Published |
03.05.2012
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention describes antibodies that target CD40, wherein the antibodies comprise at least one modification relative to a parent antibody, wherein the modification alters affinity to an FcyR or alters effector function as compared to the parent antibody. Also disclosed are methods of using the antibodies of the invention. |
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Bibliography: | Application Number: AU20080207898 |