Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors

Monatin and certain stereoisomers of monatin, such as R,R monatin and S,R monatin, as well as salts thereof, are produced using polypeptides and biosynthetic pathways. These polypeptides and biosynthetic pathways are also useful in the production of R-2-hydroxy-2-(indoly-3-ylmethyl)-4-keto glutaric...

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Main Authors BRAZEAU, BRIAN J, KOLLMANN, SHERRY R, SANCHEZ-RIERA, FERNANDO A, LAPLAZA, JOSE M, GORT, STEVEN J, HICKS, PAULA M, DE SOUZA, MERVYN L, MCFARLAN, SARA C, SOLHEID, CHRISTOPHER
Format Patent
LanguageEnglish
Published 20.06.2013
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Summary:Monatin and certain stereoisomers of monatin, such as R,R monatin and S,R monatin, as well as salts thereof, are produced using polypeptides and biosynthetic pathways. These polypeptides and biosynthetic pathways are also useful in the production of R-2-hydroxy-2-(indoly-3-ylmethyl)-4-keto glutaric acid, an intermediate that is formed in certain monatin synthesis pathways, including some biosynthetic pathways.
Bibliography:Application Number: AU20070342275