Method for improving pharmacokinetics
The present invention provides pharmaceutical compositions and methods for improving the pharmacokinetics of drugs which may be metabolized by cytochrome P450 monooxigenase, the method may comprise co-administering a compound of formula I, with the drug; when the compound of formula I comprises an a...
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Main Authors | , , |
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Format | Patent |
Language | English |
Published |
26.02.2009
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention provides pharmaceutical compositions and methods for improving the pharmacokinetics of drugs which may be metabolized by cytochrome P450 monooxigenase, the method may comprise co-administering a compound of formula I, with the drug; when the compound of formula I comprises an amino group, pharmaceutically acceptable ammonium salts thereof, wherein R1 may be, for example, H1 (HO)2P(O)-, (NaO)2P(O)-, alkyl-CO- or cycloalkyl-CO-, wherein X may be, for example, F, Cl, and Br, and wherein R2 and R3 are as defined herein. |
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Bibliography: | Application Number: AU20070287353 |