Quinoline derivatives

The invention relates to new quinoline derivatives which are active CLK-1 inhibitors. More specifically, the CLK-1 inhibitors of the invention are compounds of formula (A). The invention also relates to pharmaceutical compositions comprising such compounds and to methods for the prophylaxis and/or t...

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Bibliographic Details
Main Authors MARIE-PIERRE GUIMOND, KEVIN MCBRIDE, STEVEN LEONARD HAYES, IRENEJ KIANICKA, YING WANG, JULIAN SMITH, SIEGFRIED HEKIMI, GUY SEVIGNY, ABDELMADJID K. HIHI, DANIEL DUMAS
Format Patent
LanguageEnglish
Published 07.02.2008
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention relates to new quinoline derivatives which are active CLK-1 inhibitors. More specifically, the CLK-1 inhibitors of the invention are compounds of formula (A). The invention also relates to pharmaceutical compositions comprising such compounds and to methods for the prophylaxis and/or treatment of disorders or their associated symptoms for which the inhibition of CLK-1 is beneficial.
Bibliography:Application Number: AU20070280984