Medicament for the enhancement of cognitive function and neuroprotection

The invention relates the use of 4-chloro-5-{2-[4-(6-fluoro-1,2- benz[d]isoxazole-3-yl)piperidin-1-yl]ethyl-amino}-2-methyl-3- (2H) pyridazinone of the Formula (I) or pharmaceutically acceptable salts thereof for the preparation of medicaments suitable for the improvement of cognitive function or ob...

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Main Authors KERTESZ, SZABOLCS, MORICZ, KRISZTINA, GIGLER, GABOR, SIMIG, GYULA, KOMPAGNE, HAJNALKA, SZENASI, GABOR, AGOSTON, MARTA, HARSING, LASZLO GABOR, LEVAY, GYORGY, BARKOCZY, JOZSEF, GACSALYI, ISTVAN
Format Patent
LanguageEnglish
Published 09.08.2012
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates the use of 4-chloro-5-{2-[4-(6-fluoro-1,2- benz[d]isoxazole-3-yl)piperidin-1-yl]ethyl-amino}-2-methyl-3- (2H) pyridazinone of the Formula (I) or pharmaceutically acceptable salts thereof for the preparation of medicaments suitable for the improvement of cognitive function or obtaining neuroprotective effect. The medicaments containing 4-chloro-5-{2-[4-(6-fiuoro-1,2- benz[d]isoxazol-3-yl)piperidin-1-yl]ethyl-amino}-2-methyl-3- (2H) pyridazinone of the Formula (I) or therapeutically acceptable salt thereof can be used for the treatment or prevention of neuronal death, mental decline, sclerosis multiplex, Creuzfeld-Jacobs disease, Huntingdon- syndrome, amyotrophic lateral sclerosis, Parkinson-disease, memory disturbance, loss of memory, amnesia, stroke or for the improvement of memory function or learning ability.
Bibliography:Application Number: AU20070270910