Antagonists of the vanilloid receptor subtype 1 (VR1) and uses thereof

The present invention is directed to compounds of formula (I), wherein variables X, X, Y, R, R1, R, R, A, A, A, and A are as defined in the description, and methods of use to treat pain, neuropathic pain, allodynia, pain associated with inflammation or an inflammatory disease, inflammatory hyperalge...

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Bibliographic Details
Main Authors GOMTSYAN, ARTHUR R, KOENIG, JOHN R, BROWN, BRIAN S, LEE, CHIH-HUNG
Format Patent
LanguageEnglish
Published 07.06.2012
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention is directed to compounds of formula (I), wherein variables X, X, Y, R, R1, R, R, A, A, A, and A are as defined in the description, and methods of use to treat pain, neuropathic pain, allodynia, pain associated with inflammation or an inflammatory disease, inflammatory hyperalgesia, bladder overactivity, and urinary incontinence.
Bibliography:Application Number: AU20070238071